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Principal Clinical Scientist
Remote (Global)
$40 – $80/hr
May 22, 2026
Job description
Principal Clinical Scientist (AI Training)
About the Role
What if your deep expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about biomedical evidence?
We're looking for a Principal Clinical Scientist to bring senior-level clinical rigor to cutting-edge AI research. In this role, you'll help ensure the clinical data powering next-generation AI systems meets the exacting standards expected in real-world regulatory submissions — and that the AI itself reasons about that data with scientific integrity.
This is a fully remote, flexible contract role built for senior clinical professionals who want to work at the intersection of rigorous science and frontier technology.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training and evaluation
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent)
- Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
- Provide structured expert feedback that directly improves how AI models reason about clinical trial data, outcomes, and endpoints
- Work independently and asynchronously — on your own schedule, at your own pace
Who You Are
- Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data in the context of major regulatory agencies (FDA, EMA, or equivalent)
- Strong foundation in clinical research methodology, biostatistics, translational science, or a closely related discipline
- Rigorous, detail-oriented thinker who holds AI-generated outputs to the same standards as real-world submissions
- Clear and precise written communicator who can articulate complex scientific reasoning effectively
Nice to Have
- Prior experience with data annotation, data quality review, or AI evaluation workflows
- Background in pharmacovigilance, medical affairs, or clinical operations
- Exposure to real-world evidence (RWE) or post-market clinical studies
- Familiarity with AI tools or scientific content evaluation platforms
Why Join Us
- Work directly on frontier AI systems being built alongside the world's leading AI research labs
- Shape how AI understands and evaluates real-world clinical evidence — a genuinely rare opportunity
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, impactful scientific work
- Potential for ongoing work and contract extension as new projects launch
Apply now
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